http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0399054-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f9af914ed2fb00cd4f1b8b1a28964e4 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-08 |
| filingDate | 1989-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb344b195e7dd191d141eefa358c6562 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9224586ad3bfe4647596069ada282123 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e062f789707dc0b50bb03fb63a52ad1 |
| publicationDate | 1991-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0399054-A |
| titleOfInvention | Production of granular cysteamine hydrochloride |
| abstract | PURPOSE: To obtain the title granular compound reduced in occurrence of fine powder and excellent in storage stability, etc., by melting cysteamine hydrochloride obtained from a sulfuric acid ester of 2-aminoethanol by two synthetic processes at a specific temperature, adding the melt dropwisely onto a corrosion resistant substrate having a specific temperature, and cooled and solidified the melt. n CONSTITUTION: A sulfuric acid ester of 2-aminoethanol is reacted with carbon disulfide in the presence of an alkali hydroxide to give 2-mercaptothiazoline, which is then hydrolyzed with hydrochloric acid to afford cysteamine hydrochloride. Then the cysteamine hydrochloride is heated to ≥68°C, preferably at 70-100°C and the melt is added dropwisely onto a corrosion resistant substrate cooled to ≤65°C, preferably 40-10°C and cooled and solidified to provide the granular cysteamine hydrochloride reduced in occurrence of fine powder, excellent in operating properties on handling without forming a mass even during the storage, excellent in solubility to inorganic acid and organic liquid, useful as a raw material for medicine, agricultural chemical, etc., and having a uniform granular size. n COPYRIGHT: (C)1991,JPO&Japio |
| priorityDate | 1989-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.