http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0381274-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6831b19bfc354357342f7c7da79fc162 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C62-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C62-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-92 |
filingDate | 1989-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d43de0ae06f3bd15bb4d281851c7057c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e3f493406718635eaeb06aacf79e542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28eb70ffa66b2fec12b192e36773fe10 |
publicationDate | 1991-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H0381274-A |
titleOfInvention | Production of naphthalene derivative and synthetic intermediate thereof |
abstract | PURPOSE: To obtain the title compound useful as an antilipemic agent by one process simply by reacting an oxo-tetrahydronaphthalene compound with a reactive derivative in carboxyl group of formic acid and treating the reaction product with an acid. n CONSTITUTION: An oxo-tetrahydronaphthalene compound shown by formula I (ring A is substituted or nonsubstituted benzene ring; one of R 1 and R 2 is H or lower alcohol and the other is lower alkoxy), an enol type tautomer thereof or a reactive derivative in carboxyl group thereof and a reactive derivative in carboxyl group of formic acid are used as starting raw materials and reacted preferably in the presence of a condensation agent (e.g. alkali metal alkoxide) in a solvent such as benzene at 30-50°C. Then the reaction product is treated with an acid (e.g. trifluoroacetic acid or sulfuric acid) and optionally the reaction product is made into a salt thereof to give a compound shown by formula II. n COPYRIGHT: (C)1991,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9807705-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6030967-A |
priorityDate | 1989-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.