http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0377852-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_88fbcd2a70a3c49d0aed69a000d55909 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2de3beee83d9c19278da409b72c777a8 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C225-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C221-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
filingDate | 1989-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09cd2566246bdd7a0c5516b1113f95c1 |
publicationDate | 1991-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H0377852-A |
titleOfInvention | Production of 3-amino-2-hydroxyacetophenone |
abstract | PURPOSE: To industrially and advantageously obtain the title compound by subjecting a 5-halo-2-hydroxy-3-nitroacetophenone used as a raw material to catalytic hydrogenation reaction in a mixed solvent of halogenated hydrocarbon and water in the presence of a Pd catalyst so as to simultaneously carry out reduction of nitro group and dehalogenation. n CONSTITUTION: A 5-halo-2-hydroxy-3-nitroacetophenone used as a raw material is subjected to catalytic hydrogenation reaction in a halogenated hydrocarbon/ water mixed solvent in the presence of a palladium catalyst so as to simultaneously carry out reduction of nitro group and dehalogenation to readily provide the 3-amino-2-hydroxyacetophene in one stage. The objective substance is useful as an intermediate of a medicine, especially for allergy. The above-mentioned method can be practiced in industrial scale and is advantageous also from the aspects of yield and operation. n COPYRIGHT: (C)1991,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108911988-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108911988-B |
priorityDate | 1989-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.