| abstract |
NEW MATERIAL:A quinone derivative shown by formula I [R 1 and R 2 are H, methyl, methoxy or R 1 and R 2 are mutually bonded to form CH=CH-CH= CH; R 3 is H or methyl; R 4 is phenyl; R 5 is hydroxymethyl or carboxyl; Z is C≡C or CH=CH; (n) is 2-10; (m) is 1-3; (k) is 0-5 with a proviso that when (m) is 2 or 3, Z and k are arbitrarily changeable with regard to the repeating unit shown in [ ]) or a hydroquinone derivative thereof. n EXAMPLE: (Z)-7-(3,5,6-Trimethyl-1,4-benzoquinon-2-yl)-7-phenyl-2-hepten-1-ol. n USE: A medicine and preventive for bronchial asthma, immediate allergy, various kinds of inflammations, arteriosclerosis, etc. n PREPARATION: A compound shown by formula II (R 6 is H, methyl, etc.; R 7 is H, hydroxyl group, etc.) is reacted with an oxidizing agent to give a compound shown by a formula I. n COPYRIGHT: (C)1991,JPO&Japio |