http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0363299-A

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filingDate 1989-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b03c54080a760cf4fcf4bb16bb1d1917
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publicationDate 1991-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H0363299-A
titleOfInvention Modified erithropoietin
abstract NEW MATERIAL:Erithropoietin modified with polymeric compound. n USE: Used as medicine for various anemia such as renal anemia according to decrease of erithropoietin production owing to renal injury continuously exhibiting erithropoietic activity. n PREPARATION: By gene technological method, gene-recombinant erithropoietin produced in CHO cell is added to a solution adjusted of dextran 40, etc., and 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloric acid, etc., is added, then subjected to coupling. Besides, the polymeric compound is preferably dextran, polyethylene glycol or amino acid polymer. n COPYRIGHT: (C)1991,JPO&Japio
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Total number of triples: 28.