http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H035437-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af17c491906d7d677939f7f2c2f7d157 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a12c1d0a13fb8c5733e0d2567a8b5928 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d52fb19b52d823bf46c8f0848c684dfc |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G21H5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-89 |
| filingDate | 1989-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82879b0e41e93a4735ae3f0cb12c01d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b88f6870efffee335b6a03571b41e93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e913a857faad804b9a819832f75f1282 |
| publicationDate | 1991-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H035437-A |
| titleOfInvention | Production of 11c ketene and automatic apparatus therefor |
| abstract | PURPOSE: To advantageously obtain ketene containing a radioisotope by reacting carbon dioxide containing the radioisotope with a specific organometallic reagent, decomposing the excess above-mentioned reagent, then evaporating the decomposition product to dryness, subsequently adding an acid and thermally decomposing the resultant organic acid. n CONSTITUTION: An organometallic reagent 7 expressed by the formula RM or RMX (R is organic group; M is alkali metal; MX is alkaline earth metal) is added to carbon dioxide 12 containing a radioisotope expressed by formula I ( 11 C is radioisotope) to form an organometallic salt expressed by formula II or III. Water, etc., 10 are then added thereto to decompose the excess above-mentioned reagent. The water, etc., are evaporated under reduced pressure to evaporate the aforementioned metal salt to dryness. An acid is further added thereto to convert the above-mentioned metal salt into an organic acid expressed by formula IV, which is then thermally decomposed to efficiently and safely afford a radioactive ketone, expressed by formula V and useful for diagnosis, etc., using position emission CT using an automatic production apparatus capable of automatically controlling the aforementioned series of operations through solenoid valves (V 4 ), (V 11 ), (V 12 ), (V 13 ), etc., preferably connecting respective vessels 12, 7, 10, 11, etc., to a reaction vessel 6. n COPYRIGHT: (C)1991,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H08201588-A |
| priorityDate | 1989-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.