http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0352886-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a452aeb7f766d55db6921d784361b891 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-455 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
filingDate | 1989-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d8928cb38ac4c6e46f87e5acf45811e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18b293fbe125c52de69f694e511d23d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_705dadb80ed2273a02218febcc2ae366 |
publicationDate | 1991-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H0352886-A |
titleOfInvention | 1,4-dihydropyridine composition |
abstract | PURPOSE: To obtain the title composition useful for circulatory diseases, increasing water-solubility, providing sufficient concentration in blood by blending a dihydropyridine derivative with a polyethylene glycol and a surfactant in a specific ratio, dissolving and uniforming. n CONSTITUTION: (A) 1 pt.wt. 1,4-dihydropyridine derivative [e.g. 2,6-dimethyl-4-(2- trifluoromethylphenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 2-(4-chloro-6- methylquinoline-3-carboxy) ethylmethyl ester] shown by the formula (R 1 is nitro or trifluoromethyl; R 2 is lower alkyl; R 3 is 6-membered heterocyclic ring containing one N atom in the ring, may be substituted with O, halogen, OH, haloalkyl, etc., or further the group may be condensed with carbon homocyclic replaceable with lower alkyl, etc.) is blended with (B) 5-70 pst.wt. polyethylene glycol and (C) 1-70 pts.wt. surfactant having ≥12 HLB, dissolved and uniformed to give the aimed composition. n COPYRIGHT: (C)1991,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6840682-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6533464-B1 |
priorityDate | 1989-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.