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filingDate 1989-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be09835952ad8358baa9bf2bfa6f49be
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publicationDate 1991-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H0352880-A
titleOfInvention Production of (s)-gamma-hydroxymethyl alpha,beta-butenolide
abstract PURPOSE: To obtain the title compound useful as a synthetic raw material for drugs such as prostaglandin and anti-leukemic lignan inexpensively and in high yield by oxidizing levoglucosenone as a starting raw material with a peracid in an organic solvent. n CONSTITUTION: Levoglucosenone as a raw material is oxidized with a peracid in an organic solvent at room temperature while stirring to give the objective compound. Peracetic acid, m-chloroperbenzoic acid, magnesium monoperoxyphthalate.6 hydrate, etc., may be cited as the peracid. The amount of the peracid used is 1.0-3.0mols based on 1mol levoglucosenone. Acetic acid, methylene chloride, methanol, etc., are properly used as the organic solvent. Levoglucosenone can be inexpensively and readily obtained by thermally decomposing cellulose. n COPYRIGHT: (C)1991,JPO&Japio
priorityDate 1989-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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