http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0347165-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_630b360599ea5cf4b5bcbc0c6c0a3e2d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-323 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 |
| filingDate | 1989-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c52a90102dcf356f5b8fa023e9b7c62c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_932d251d76dba73f2f7d4d1810c7f646 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_819c3af3ede99c87993e74c6078992a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d05e539bce111c4e4179af99cfca7a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ede7f28c6f8238ea9232d68af687875 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1f6a931a6626138a5833628c96c268a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41240a10abde872cb5030f04e61e9166 |
| publicationDate | 1991-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0347165-A |
| titleOfInvention | Pyrrole carboxylic acid derivative |
| abstract | NEW MATERIAL:A compound expressed by formula I (R 1 is H, 5-25C alkyl or alkenyl; R 2 is H, phenyl or 1-10C alkyl which may be replaced; R 3 is H, 5-25C alkyl or alkenyl) or salt thereof. n EXAMPLE: 5-Tetradecylpyrrole-2-carboxylic acid ethyl ester. n USE: The compound expressed by formula I or salt thereof has excellent lipid lowering action capable of simultaneously and strongly lowering triglyceride and cholesterol in blood and is useful as a remedy, etc., for hyperlipemia. n PREPARATION: For example, a compound expressed by formula II (X is halogen) obtained by reacting pyrrole with methyl or ethyl magnesium halide is reacted with an acyl chloride expressed by formula III (R 4 is 4-24C alkyl) and the resultant compound expressed by formula IV is subjected to Wolf-Kishner reduction to afford 2-alkylpyrrole expressed by formula V. Then the compound expressed by formula V is reacted with a Grignard reagent and further reacted with ethyl chlorocarbonate and as necessary the resultant product is hydrolyzed to provide the compounds expressed by formula VII and formula VIII. n COPYRIGHT: (C)1991,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100460414-B1 |
| priorityDate | 1988-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.