| abstract |
PURPOSE: To obtain preventive and curing drug exhibiting synergistic effect and capable of suppressing protozoa disease with practically possible range of administration dose by combining plant component having antiprotozoal activity and ionophores antibiotic. n CONSTITUTION: The aimed preventive and curing drug for protozoa disease is composed of (A) plant component having antiprotozoal activity, e.g. condensed type tannin, resinous glucoside, magnolol, derivative of said substances or plant body containing said substances and (B) ionophores antibiotic, e.g. monensin, narasin, salinomycin, lasalocid, carriomycin or maduramicin. Said drug is preferably administrated with adding to feed and the adding amount is suitably 0.01-1.5wt.%, preferably 0.02-1.0wt.% the component A and 1/2 amount-same amount of normally admired adding amount of ionophores antibiotic to feed of the component B. By said method, using amount of ionophores antibiotic, and also possibility of acquirement of resistance to ionophores, are able to be reduced. n COPYRIGHT: (C)1991,JPO&Japio |