http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0331288-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14b02369b953bf4ebd31190c8cb63473 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535 |
| filingDate | 1989-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46675a6e36606026dc3d89ac8898923d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6c6271aa7a69f61a193ad6881902d28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c2c209420e4fad000e1eac5c1861bda http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee727517e86a41e8550b8a01b821e983 |
| publicationDate | 1991-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0331288-A |
| titleOfInvention | Production of 9,1-epoxymethano-7-fluoro-8-(4-methyl-1-piperazinyl)-5-oxo-5h-thiazolo(3,2-a)quinoline-4-carboxylic acid-hydrochloride in specific crystal form |
| abstract | PURPOSE: To readily and surely obtain the subjective hydrochloride useful as an antibacterial agent without containing a compound of other crystal forms by treating a specific carboxylic acid with hydrochloric acid and heating the resultant hydrochloride together with ethanol under specific conditions. n CONSTITUTION: 9,1-Epoxymethano-7-fluoro-8-(4-methyl-1-piperazinyl)-5-oxo-5H- triazolo[3,2-a]quinoline-4-carboxylic acid is treated with hydrochloric acid to form a hydrochloride and 1 pt.wt. of the hydrochloride together with 1-40 pts.wt. of ethanol, is heated at 40°C to the boiling point of ethanol to afford the objective hydrochloride having at least six diffraction lines of 6.7±0.2, 10.3±0.2, 10.5±0.2, 16.1±0.2, 20.7±0.2 and 21.1±0.2 between 5-22 degree of diffraction angle 2θ in a X-ray diffraction spectrum with a reflective powder method using Cu-Kα radiation. n COPYRIGHT: (C)1991,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011031745-A1 |
| priorityDate | 1989-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.