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filingDate 1990-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_923cc349ea999d26f19639d4e251c035
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publicationDate 1991-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H03294281-A
titleOfInvention Method for producing oxazopyrroloquinolines
abstract PURPOSE: To obtain the subject compound useful as a drug and having no renal toxicity by culturing specific bacteria in a medium containing methanol as a C source and subsequently adding an amino acid, etc., to the culture solution to convert pyrroloquinolinequinone into an oxazopyrroloquinoline compound in the presence of oxygen. n CONSTITUTION: Bacteria (e.g. Methylobacillus glycogenes) having an ability to produce pyrroquinolinequinone is cultured in a medium containing methanol as a C source to prepare a culture solution containing the pyrroquinolinequinone. The culture solution is mixed with various amino acids and/or monomethylamine and converted into an oxazopyrroloquinoline compound in the presence of oxygen to provide the objective compound. n COPYRIGHT: (C)1991,JPO&Japio
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