http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H03292890-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_52a65b677bbedbe7bf090dd556a7cc43 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| filingDate | 1990-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aaeccc654e7c1be5352d184b278f54d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51e831f3661ff88cdf33b5ced99ac9cb |
| publicationDate | 1991-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H03292890-A |
| titleOfInvention | Production of optically active 3-aryl-3-hydroxypropionic acid alkyl ester |
| abstract | PURPOSE: To produce a large amount of the subject compound in high purity and efficiency by treating a 3-aryl-3-hydroxypropionic acid alkyl ester (AHPA) with an esterase originated from microorganisms, etc. n CONSTITUTION: A reaction liquid is produced by mixing a substrate consisting of an AHPA of formula I (R 1 to R 5 are H, OH, 1-4C alkoxy or benzyloxy; R 6 is alkyl) and a fatty acid vinyl ester or triglyceride at a molar ratio of 1:(0.5-10) and dispersing the mixture in a solvent such as n-hexane. An esterase originated from microorganisms of genus Pseudomonas, etc., is added to the reaction liquid and reacted at 10-150°C for 1-1,000hr to effect the ester interchange with the triglyceride to obtain an optically resolved product. The product is filtered, distilled under reduced pressure and subjected to a column chromatography to separate an optically active 3-aryl-3-acyloxypropionic acid alkyl ester and produce an optically active 3-aryl-3-hydroxypropionic acid alkyl ester of formula II [e.g. (-)-3-(2-methoxyphenyl)-3-hydroxypropionic acid methyl ester]. n COPYRIGHT: (C)1991,JPO&Japio |
| priorityDate | 1990-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.