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filingDate 1990-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_673121aaeb2ef60b15b215fcd2720090
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publicationDate 1991-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H03291224-A
titleOfInvention Drug having improved absorptiveness
abstract PURPOSE: To obtain the subject remedy for diabetes mellitus having an improved absorptiveness in the digestive tube by solid dispersing a benzoxazole derivative or its salt in a water soluble polymer material showing a solid state at the ordinary temperatures or by dissolving the above mentioned compound in a water soluble liquid polymer material. n CONSTITUTION: A compound, e.g. {5-[2,4-dioxothiazolidin-5-yl) methyl]-2-[4-(dimethylamino)benzyl]benzoxazole} of the formula (R is phenyl or naphthyl which may have substituent; Alk is lower alkylene) or a pharmacologically allowable salt thereof is solid dispersed or dissolved in a water soluble polymer material to produce the objective drug for remedy of diabetes mellitus having an excellent absorptiveness. As the water soluble polymer material, polyethylene glycol, polyvinyl pyrrolidone, methylcellulose, gelatin, etc., are used and the amount thereof used is preferably 3-20 pts.wt. and 30-50 pts.wt. based on 1 pts.wt. active component respectively in case of a solid state and a solution. n COPYRIGHT: (C)1991,JPO&Japio
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