| abstract |
NEW MATERIAL:A compound shown by formula. n USE: A reaction catalyst for asymmetric hydrogenation, asymmetric isomerization, asymmetric silylation, etc. n PREPARATION: o-Toluidine is treated with acetic anhydride to acetylate amino group, then nitrated with nitric acid and hydrolyzed with an aqueous solution of hydrochloric acid to give 2-amino-3-nitrotoluene. Then 2-amino-3-nitrotoluene is diazotized with sodium nitrite in the presence of sulfuric acid and then successively treated with an aqueous solution of potassium iodide. The reaction product is reacted in the presence of copper powder at 200°C to give 6,6'- dimethyl-2,2'-dinitro-1,1'biphenyl. This compound is hydrogenated, the reaction product is dissolved in hydrobromic acid, reacted with sodium nitride, the reaction solution is blended with sodium nitrite and methylene chloride and water, the organic layer is concentrated and purified, the product is dissolved in THF, reacted with t-butyllithium, refluxed under heating, recrystallized, dissolved in a solvent and mixed with triethylamine, trifluorosilane, etc. n COPYRIGHT: (C)1991,JPO&Japio |