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filingDate 1990-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a6301ab0737d74763d0adfc085fe9f6
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publicationDate 1991-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H03258722-A
titleOfInvention Drug containing vitamin d3 or family compound
abstract PURPOSE: To obtain the subject drug stable to light, heat and air oxidation by uniformly blending and dispersing a vitamin D 3 unstable at the room temperature together with dibutyl-hydroxytoluene or butyl-hydoxyanisole in a vehicle such as crystalline cellulose. n CONSTITUTION: A Vitamin D 3 (especially preferably vitamin D 3 or 1α- hydroxyvitamin D 3 ) is dispersed in crystalline cellulose or crystalline cellulose- sodium carboxymethylcellulose using dibutyl-hydroxytoluene or butyl- hydroxyanisole to obtain the objective drug containing an excellently dispersed stable vitamin D 3 . The resultant drug obtained by the above-mentioned method is almost free from reduction of vitamin D 3 content for a long period. The preparation process is simple and the above-mentioned method is advantageous therefor. n COPYRIGHT: (C)1991,JPO&Japio
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