| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_065fe7c4146d471ac47823ff7c1d911f |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate |
1989-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bba25f299c01a8ce5bd1883a939ec7d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2477c2ec8f4ca4ef58bc2fa7bba58477
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40799925b7c9576ef4fd437249965b91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b6e7c478bccfa866405fac18d75dfec |
| publicationDate |
1991-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-H0324047-A |
| titleOfInvention |
Production of phenylmalonic acid monoanilide derivative and 3-phenyl-2-quinolone derivative |
| abstract |
NEW MATERIAL:The compound of formula I (X and Y are H or 1-3C alkoxy; Z is 1-3C alkoxy). n EXAMPLE: 2-(3-Methoxy-phenylcarbamoyl)-2-(2,4-dimethoxyphenyl)acetic acid. n USE: Useful as a drug or its synthetic intermediate. n PREPARATION: The compound of formula I is produced by reacting an aniline derivative of formula II with a phenylmalonic acid monoester derivative of formula III (R is lower alkyl) in the presence of a dehydrative condensation agent (e.g. trimethylsilyl phosphite) at room temperature and removing the ester group of the product. Cyclization of the compound of formula I in the presence of a condensation agent gives a 3-phenyl-2-quinolone derivative of formula IV exhibiting osteogenesis promoting action and useful as a remedy for osteoporosis. n COPYRIGHT: (C)1991,JPO&Japio |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017097870-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1981341-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1981341-A2 |
| priorityDate |
1989-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |