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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00
filingDate 1990-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77d051b9d9fab1f8922e6415bbe6e11b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f57060966d3e01fa1a028cf9dc7753ca
publicationDate 1991-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H03236795-A
titleOfInvention Production of optically active 1,3-butanediol
abstract PURPOSE: To accelerate reaction rate and improve productivity of the title compound by reacting a mixture (BEM) of enantiomers of 1,3-butanediol with a specific microorganism in the presence of an alcohol or ketol. n CONSTITUTION: A microorganism such as Candida parapsilosis IFO 1396 bacterial strain having ability capable of asymmetrically assimilating a mixture (BEM) of enantiomers of 1,3-butanediol is inoculated into a culture medium containing glucose, yeast extract, etc., and aerobically cultured at pH3.0-9.5 and 20-45°C for 5-120hr to provide the cultured product (A). Then the ingredient A is blended with 0.1-10wt.% BEM and 0.05-1wt.% alcohol such as ethanol, ethylene glycol or 1-propanol or ketol such as dihydroxyacetone to afford the reaction product liquid (B). Then the ingredient B is reacted at pH3-10 and 10-60°C for 1-120hr to provide the reaction product (C). Then the ingredient C is separated from the bacterial cell and then extracted and purified with column chromatography, etc., to provide the optically active 1,3-butanediol. n COPYRIGHT: (C)1991,JPO&Japio
priorityDate 1990-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 26.