http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H03223244-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2de3beee83d9c19278da409b72c777a8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-357 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate | 1990-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8eeae1b777201c1ca98d195cb4e84ad1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1abb4e25b62532fcdfaa461656ca695 |
| publicationDate | 1991-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H03223244-A |
| titleOfInvention | 5-hetero-6-oxo-pge derivative, its production and drug containing the same derivative |
| abstract | NEW MATERIAL:A compound shown by formula I [R 1 is COOR11 (R 11 are H, alkyl, cycloalkyl, admantyl, etc.) hydroxymethylcarbonyl, hydroxymethyl, CO-AA (AA is amino acid residue); Z is O, S or NR 21 (R 21 is H or alkyl); R 2 is single bond or 1-4C alkylene; R 3 is 1-7C alkyl, 4-7C cycloalkyl which may be replaced, phenyl or phenoxy which may be replaced], an atoxic salt and a cyclodextrin salt thereof. n EXAMPLE: 5-Oxa-6-oxo-17S,20-dimethyl-PGE 1 . n USE: Having PG-like activity, especially strong cell protecting action and useful for preventing and treating various diseases caused by cytotoxicity. n PREPARATION: For example, a compound shown by formula II (R 4 is tert.- butylmethylsilyl, 2-tetrahydropyranyl, etc.) is hydrolyzed under an acidic condi tion and optionally further esterified or amidated to give a corresponding com pound shown by formula I. n COPYRIGHT: (C)1991,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0003980-A1 |
| priorityDate | 1989-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.