http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H03218379-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59e1d955a7b1560dc68cf7fd800e8fac |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P23-00 |
filingDate | 1990-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88f179306c7aa437efcaf0f30781aeb9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_baef81d3059f276b0bd35f3910fc0994 |
publicationDate | 1991-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H03218379-A |
titleOfInvention | Novel morphine derivative |
abstract | NEW MATERIAL:The compound of formula I (R 1 is H, lower alkyl or lower alkanoyl; R 2 is H, lower alkylthio, aryl, lower alkoxycarbonyl-alkyl or lower alkyl; R 3 is lower cycloalkylmethyl). n EXAMPLE: 3-Acetyl-6β-methylthio-N-cyclopropylmethylnormorphine. n USE: A medicine having excellent analgesic activity and narcotic antagonistic action. n PREPARATION: A cycloalkylmethylnormorphine of formula III derived from normorphine of formula II is converted to a ditosylate compound, reacted with a compound of formula R 5 SX (R 5 is lower alkyl, etc.; X is alkali metal), hydrolyzed and, as necessary, acylated or alkylated at the 3-site. n COPYRIGHT: (C)1991,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1758452-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008501036-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02080918-A1 |
priorityDate | 1989-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.