| abstract |
PURPOSE: To achieve quick internal formation of a bone by using a biocompatible carrier which comprises a liquid polyhydroxy compound or its derivative and demineralized powdered bones to constitute a fluid composition to be imparted to the defective part of the bone. n CONSTITUTION: A fluid composition, which comprises a biocompatible carrier selected from a group consisting of a liquid polyhydroxy compound or its derivative, a solid polyhydroxy compound and a solution of its derivative, and a mixture thereof and demineralized powdered bones, is imparted to the defective part of a bone. Demineralization of the bone is effected by first crushing the bone to desired average grain sizes (0.1 to about 1.2cm), then degreasing/ sterilizing the bone with an ethanol aqueous solution, and demineralizing it with an inorganic acid such as hydrochloric acid or with an organic acid such as peracetic acid. Thus, rapid internal formation of the bone can be brought about on the defective part of the bone. n COPYRIGHT: (C)1991,JPO |