| abstract |
NEW MATERIAL: A compound of formula I [m is 1-3; Ar and Ar' are each thienyl, (substd.) phenyl, etc.; X is H; X' is H, OH, forms C-C bond linked with X", etc.; X" is H, forms C-C bond with X'; Y is N, C(X"); Q is H, 1-4C alkyl, -(CH 2 ) q -Am' (q is 2, 3; Am' is piperidino, 4benzylpiperidino, etc.); R is H, methyl, (CH 2 )N-L (n is 2-6; L is H, amino); T is -C(O)-, -C(W)-NH- (W is O, S); Z is H when T is -(=O)-, M, OM, and when T is -C(=W)-NH, M (M is H, 1-6C alkyl)]. n EXAMPLE: N-[4-(4benzylpiperidin-1yl)-2-(3,4dichlorophenyl)butyl]2,4- dichlorobenzamide. n USE: A therapeutic agent for pains, allergies, inflammation, cardiac insufficiencies, digestive troubles or respiratory diseases. n PROCESS: A compd. of formula II is reacted with a compd. of formula III. n COPYRIGHT: (C)1991,JPO |