http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H03200739-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f8cfa5aee4410611b5c562275c9f8e3 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-732 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-08 |
filingDate | 1989-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d5959db779fb20c40267cc0d3bea243 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb5f410677b405108e5d830b3eff0986 |
publicationDate | 1991-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H03200739-A |
titleOfInvention | Optically active 2-hydroxy-4-phenyl butyric acid and production of ester of same butyric acid |
abstract | PURPOSE: To make possible to industrially produce the subject optically active compound useful as a synthetic raw material of various medicinal drugs by subjecting optically active 2-hydroxy-4-phenyl-3-butenic acid to hydrogenation in the presence of a solvent and further esterifying, as desired. n CONSTITUTION: Optically active 2-hydroxy-4-phenyl-3-butenic acid is subjected to hydrogenation in a suitable solvent such as ethyl acetate or a mixed solvent of methanol and toluene in the presence of a suitable catalyst such as palladium- carbon at a temperature of, e.g. 0-300°C, preferably 10-70°C under a pressure of from normal pressure to 200kg/cm 2 , preferably under normal pressure according to a well-known method of usual catalytic hydrogenation reaction in a heterogeneous system to industrially advantageously obtain optically active 2-hydroxy-4-phenyl butyric acid. Next, said acid is esterified by using an alcohol corresponding to the aimed compound in a usual method to industrially advantageously obtain the aimed optically active 2-hydroxy-4-phenyl butyric acid alkyl ester. n COPYRIGHT: (C)1991,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0759424-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100363824-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7094920-B2 |
priorityDate | 1989-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.