http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H03200739-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-36
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-08
filingDate 1989-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d5959db779fb20c40267cc0d3bea243
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb5f410677b405108e5d830b3eff0986
publicationDate 1991-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H03200739-A
titleOfInvention Optically active 2-hydroxy-4-phenyl butyric acid and production of ester of same butyric acid
abstract PURPOSE: To make possible to industrially produce the subject optically active compound useful as a synthetic raw material of various medicinal drugs by subjecting optically active 2-hydroxy-4-phenyl-3-butenic acid to hydrogenation in the presence of a solvent and further esterifying, as desired. n CONSTITUTION: Optically active 2-hydroxy-4-phenyl-3-butenic acid is subjected to hydrogenation in a suitable solvent such as ethyl acetate or a mixed solvent of methanol and toluene in the presence of a suitable catalyst such as palladium- carbon at a temperature of, e.g. 0-300°C, preferably 10-70°C under a pressure of from normal pressure to 200kg/cm 2 , preferably under normal pressure according to a well-known method of usual catalytic hydrogenation reaction in a heterogeneous system to industrially advantageously obtain optically active 2-hydroxy-4-phenyl butyric acid. Next, said acid is esterified by using an alcohol corresponding to the aimed compound in a usual method to industrially advantageously obtain the aimed optically active 2-hydroxy-4-phenyl butyric acid alkyl ester. n COPYRIGHT: (C)1991,JPO&Japio
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priorityDate 1989-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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