http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H03178996-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f57eb55dc7fa8626ece4816e576bacc |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005 |
filingDate | 1989-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2cb01695dbcb5593b359d84edaab88d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2260858a1fef4b292eb4e36f6fc1fe69 |
publicationDate | 1991-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H03178996-A |
titleOfInvention | Growth factor |
abstract | NEW MATERIAL:A growth factor contained in the culture supernatant of a fibroblast-like cell originated from chronic rheumatism synovial cell and having the following properties. The mol.wt.: 50000-70000, not having affinity to heparin, stable on thermal treatment at 56°C for 30min and promoting the growth of vascular endothelial cell. n USE: A treatment-promoting drug for burns and wounds, a remedy for angiopathy, or a remedy or diagnostic agent for chronic rheumatism and solid tumors. n PREPARATION: For example, synovial cell is collected from the knee arthrosis of a chronic rheumatism patient, finely cut and treated with trypsin in a buffer solution. Cells contained in the supernatant are collected, cultured in a medium and cloned by a limiting dilution analysis. The fibroblast-like cells are cultured and the supernatant of the cultured solution is concentrated and purified by a high performance liquid chromatography to provide the growth factor having a mol.wt. of 50000-70000. n COPYRIGHT: (C)1991,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6518255-B2 |
priorityDate | 1989-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.