http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H03176490-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D463-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D463-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D463-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate | 1990-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cb23477dc6b6abcc8592b812e23319c |
| publicationDate | 1991-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H03176490-A |
| titleOfInvention | (1-alkyl substituted) and (1,1-dialkyl substituted) carbacephalosporins |
| abstract | NEW MATERIAL: A compound (salt) of formula I [A is H, an amino-protecting group, acyl, etc.; R 1 and R 2 are each H, a C 1-4 alkyl, etc.; R 3 is H a halogen, C 1-6 alkyl, (substd.) phenyl, etc.; R 4 is H, a carboxyl-protecting group, etc.; R 5 is H, a C 1-4 alkoxy, etc.]. n EXAMPLE: 5,5-Dimethyl-3-[(methylsulfonyl)oxy]-8-oxo-7-[(phenoxyacetyl)amino]-1 azabicyclo[4.2.0]octa-2-ene-carboxylic acid. n USE: Antibacterial agents effective against resistant microorganisms. n PROCESS: For example, 2,2-dimethyl-4-pentenal is reacted with benzylamine and then with 2-oxo-4-phenyl-3-oxazolidone acetyl chloride to give a compound of formula II. The product is hydrolysed to give an azetidinone compound of formula III, and the amino group in the product is protected. The protected product is oxidized, reacted with Masamune reagent and subjected to ring closure to give the compound of formula I. n COPYRIGHT: (C)1991,JPO |
| priorityDate | 1989-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.