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filingDate 1989-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e20bf3aefc3b5f5f7e36727913facec7
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publicationDate 1991-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H03169869-A
titleOfInvention Dioxopiperazine derivative
abstract NEW MATERIAL:A dioxopiperazine derivative of formula I [R 1 and R 2 are each H, lower alkyl, aliphatic acyloxyalkyl, alkoxycarbonyloxyalkyl, (substituted) benzoyloxyalkyl, phenylacetyloxyalkyl, phenoxyacetyloxyalkyl, aromatic heterocyclic carbonyloxyalkyl or aromatic heterocyclic acetyloxyalkyl]. n EXAMPLE: 1,2-bis(4-pivaloyloxymethyl-3,5-dioxopiperazine-1-yl)cyclohexane. n USE: Having antitumor effect, thus useful as a carcinostatic agent. Capable of oral administration. n PREPARATION: As shown in the reaction formulas, using as starting materials, cyclohexanediaminetetraacetic acid of formula II and ethyl carbamate, the objective compound of the formula I can be obtained in three steps. n COPYRIGHT: (C)1991,JPO&Japio
priorityDate 1989-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 26.