| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af737d167c026fd865fb68df681ea49a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-275
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-30 |
| filingDate |
1990-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94d71575c42d20db2a998b270f6d10d4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6ec5e60207330c6999dd2973a629132
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9eae36e329c187d9fcdc74dda71677e7 |
| publicationDate |
1991-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-H03169844-A |
| titleOfInvention |
Stable polymorphic form of (e)-n,n-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide and process for its preparation |
| abstract |
Stable and crystallographically essentially pure polymorphic form A of (E)-N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitro-phenyl)acrylamide may be prepared by crystallizing crude synthesis product from lower aliphatic carboxylic acid such as formic or acetic acid with a catalytic amount of hydrochloric or hydrobromic acid added. The product is a potent inhibitor of catechol-O-methyl-transferase enzyme (COMT). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009525971-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007527847-A |
| priorityDate |
1989-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |