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filingDate 1990-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1991-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H03169813-A
titleOfInvention Agent for treatment of pain and inflammatory disease and/or disease caused by retrovirus and having cell-protecting action and its preparation
abstract PURPOSE: To obtain the subject treating agent containing an optical isomer of an α-lipoic acid or its salt and exhibiting extremely specific and strong action compared with racemic compound. CONSTITUTION: This agent contains an R-α-lipoic acid (1,2-dithiacyclopentane-3- valeric acid) having an antiinflammatory action stronger than that of a racemic compound by a factor of 10 or an S-α-lipoic acid having an analgesic action stronger than that of a racemic compound by a factor of 5-6 or its pharmacologically permissible salt. The R- and S-α-lipoic acids have growth- suppressing action on retroviruses, especially human immunodeficiency virus HIV and are suitable for the treatment of diseases caused by the viruses. The agent is used as necessary in combination with other substances acting on retroviruses.
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007528878-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005532329-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006129841-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008524124-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007016000-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4891543-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7993676-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006083147-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2012014746-A1
priorityDate 1989-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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