| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a781c0cdfb392734abe4b0eb44e3424e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2123-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-081
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1018
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-534
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 |
| filingDate |
1990-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25e49280378bd2986282d882c706849b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8623dd0bd2da9ffc490159ea7da8679
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1d5b1cb0fd4ac68634c8c7eb55aee4a |
| publicationDate |
1991-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-H03163097-A |
| titleOfInvention |
Method of labeling protein or polypeptide with technetium-99m, produced complexe, use for imaging processing and re-preparation kit for the complexe |
| abstract |
PURPOSE: To advantageously and industrially obtain the subject compound useful for a medical imaging processing agent, etc., by introducing a thiol group into a protein or a polypeptide with a reagent capable of introducing SH groups without disulfide crosslinking reduction. n CONSTITUTION: A protein or polypeptide is labeled with technetium-99m by dissolving the protein (e.g. bovine albumin, etc.) in a phosphate buffer, etc., introducing a thiol group into the protein or polypeptide by adding and reacting a reagent (e.g. 4-mercaptobutylimidate, etc.), capable of introducing thiol groups directly without reduction steps of disulfide crosslinkage of the protein or polypeptide. Then the modified protein or polypeptide is labeled with technetium-99m by adding technetium-99m glucopeptonate prepared by reacting sodium glucopeptonate with 99m TcO 4 to protein or the polypeptide. n COPYRIGHT: (C)1991,JPO |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008525806-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2769244-B2 |
| priorityDate |
1989-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |