| abstract |
NEW MATERIAL:A compound shown by formula I [R 1 is (protected) amino; R 2 is H or organic group; R 3 is H, lower alkyl, (protected) hydroxy lower alkyl, (protected) amino lower alkyl, etc.; R 4 is H, lower alkyl, (protected) carboxy, (protected) amino or carbamoyl; Z is N or CH]. n EXAMPLE: 7β-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetamido]-3-[5-(1H- imidazo[1,2-b]pyrazolio]methyl-3-cephem-4-carboxylate. n USE: An antimicrobial agent. n PREPARATION: A compound shown by formula II, a reactive derivative at the amino group or a salt thereof is reacted with a compound shown by formula III, a reactive derivative at the carboxy group or a salt thereof. n COPYRIGHT: (C)1991,JPO&Japio |