http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H03163022-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 |
| filingDate | 1990-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_500df22f31661f9aa117e582f506d50e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a5ea1f7aee36f07e41c4cbc1b72d68a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b7bde1eb18e48313e031df650c35eb3 |
| publicationDate | 1991-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H03163022-A |
| titleOfInvention | Pharmacological composition containing prostacyclins as active ingredient |
| abstract | NEW MATERIAL:Compounds expressed by formula I (R 5 is H, 1-10C alkyl or phenyl, alicyclic group, etc., which can be substituted; R 1 is H or methyl; R 2 is unsubstituted 5-8C alkyl, phenyl, etc.; R 3 and R 4 are H, 2-7C acyl, etc.). n EXAMPLE: 9(O)-Methano-▵ 6(9) prostaglandin I 1 . n USE: Useful as a vasodilator, antistenocardiac, hypotensive, antithrombotic, antiarteriosclerotic and antimyocardial infarction agents, etc. n PREPARATION: New hydroxyprostacyclins expressed by formula II (R 3 ' and R 4 ' are 2-7C acyl, etc,; R 5 ' is 1-10C alkyl, phenyl, etc.; R 8 , R 8 ' and R 8 " are 1-7C alkyl, aryl or arylalkyl) are treated with sulfonic acid anhydride in the presence of a base and the resultant compound, as necessary, is subjected to deprotection, hydrolysis and salt-forming reaction to afford the compounds expressed by formula I. n COPYRIGHT: (C)1991,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016504286-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10308640-B2 |
| priorityDate | 1990-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.