http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H03151396-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 |
| filingDate | 1990-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a34b56361ec6215b8325f6262f23728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80efb4e5aa9fb77e0588cc29090d370c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8741b774b8ba1908022a447404f8fb20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fef360d7631262e1b165d255d7530452 |
| publicationDate | 1991-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H03151396-A |
| titleOfInvention | Axial hydroxy and mono-and dicarboxylic acid derivative exhibiting strong antitumor activity, soluble in water and solvent |
| abstract | NEW MATERIAL: A compound of formula I or formula II (A and B are each ammine, monodentate amine, etc.; A and B in the formula I are each coordinated to the Pt atom via the N atom; X and Y are each halogen; R' and R" are each H, C 1-20 alkanoyl, etc.; n' is 1 or 2; when n' is 1, then one of X' and X" is halogen and the other is C 1-10 acyloxy, and Y' and Y" are each C 1-10 acyl; when n' is 2, then X' and X" are each halogen and at least two of four Y' and Y" are cross-linked by formula III, formula IV, etc., and the rest is H, aroyl, etc.). n USE: The subject compound is useful as antitumor agents exhibiting low toxicity against kidney or bone marrow and high activity. n PROCESS: [Equatorial]dichloro[axial]dihydroxydiisopropylamine-Pt intermediate is dissolved in an acid. The solution is reacted preferably at 25°C for 1-3 weeks and extracted with ethyl ether. Then, the extract is further purified. n COPYRIGHT: (C)1991,JPO |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006521300-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009541227-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009541229-A |
| priorityDate | 1989-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.