http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H03151375-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9822bceff022feda91b10019125e70f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-357 |
| filingDate | 1989-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd8454682584fd65ab850e832c243200 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6100b17bd895360c566b1558b18d3c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66728f789dd354f1c0868e0d3e37eef8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d9e2092921d499ac8d864913500228e |
| publicationDate | 1991-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H03151375-A |
| titleOfInvention | Cyclopentane derivative and intermediate therefor |
| abstract | NEW MATERIAL:A compound expressed by formula I [R 1 and R 2 are H or silyl of R 4 R 5 R 6 Si or R 7 R 8 R 9 Si (R 4 to R 9 are 1-4C alkyl or aryl); R 3 is H or 2-7C acyl or aroyl]. n EXAMPLE: (2S)-[(4R)-2,2-Dimethyl-1,3-dioxolan-4-yl]-4-[(3Z)-(2-propynylidene) cyclopentene-2-yl]-3-butyne-1,2-diol. n USE: A carcinostatic agent having powerful cytotoxicity. n PREPARATION: A compound expressed by formula II is reacted with an acetylenic derivative expressed by formula III (R 10 is 2-7C acyl or aroyl) in the presence of a base (e.g. dimethylamine) in a solvent such as N,N- dimethylformamide at 0-50°C using a catalyst [e.g. tetrakistriphenylphosphinepalladium(O)] to afford the compound expressed by formula I. n COPYRIGHT: (C)1991,JPO&Japio |
| priorityDate | 1989-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.