| abstract |
PURPOSE: To obtain a cerebral circulation, cerebral metabolism and anamnesis improving agent having excellent anti-low oxygen action with high safety containing a substituted phenylalkanoylamine derivative. n CONSTITUTION: A compound expressed by the formula (A is 1,3-thiazolidin-3-yl, 1,2,3,6-tetrahydropyridin-1-yl, thiomorpholin-4-yl or 3-pyrrolin-1-yl; R is lower alkyl-substituted amino, pyrrolidin-1-yl, piperidino or guanidino; n is 2-6) or salt of said compound, e.g. 3-{4-[4-(N,N-dimethylamino)phenyl]butanoyl}-1,3- thiazolidine, is contained in the aimed agent as active ingredient. Administration dose of said agent is suitably in a range of 1-2000mg/day, preferably 10-200mg/ day at 1-3 times per day in a case of oral administration. n COPYRIGHT: (C)1991,JPO&Japio |