http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H03141297-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0819 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 |
| filingDate | 1990-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8124d958633b00da8b68dfe56f63f7bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_929c3a6eb47900717539f616854a9bf1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_693c4b51dfbcd3baa54d5e136a7407fc |
| publicationDate | 1991-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H03141297-A |
| titleOfInvention | Imidazole compound and use of the same as transglutaminase inhibitor |
| abstract | NEW MATERIAL: A compound of formula I or III (R 1 and R 4 are lower alkyl; R 2 and R 3 are H or lower alkyl; Pep is a peptidyl chain composed of 2-10 amino acid, it is connected with carboxyl through α-amino gp of the first amino acid, and it is finished by the amide bond by carboxyl of the last amino acid; X is negative chemical species; n is 2-5), and the salt of the same. n EXAMPLE: A compound of formula III. n USE: X III a factor inhibitor effective as a thromobolytic agent. n PROCESS: A compound of formula IV and a compound of formula V are reacted to obtain a compound of formula VI, and the obtained compound is hydrolyzed by metallic hydroxide. Then the produced acid is converted into an aromatic ester, and is converted into imidazolium salt of formula VII by CH 2 OSO 2 CF 3 . Further it is reacted with a peptide support solid phase resin poured in advance, to obtain a peptide resin, and the resin is removed from the peptide to obtain the compound of formula I or II. n COPYRIGHT: (C)1991,JPO |
| priorityDate | 1989-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.