| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f07ba5e7ff356b7eda43fdfc20eef4b0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-203
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-203
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-433
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-428
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-425
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-135
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7028
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41 |
| filingDate |
1990-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d0bff2c24626f232f8e0b5a3cc9bf26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3be5b419beddef41abbc9148825c52fc |
| publicationDate |
1991-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-H03130220-A |
| titleOfInvention |
Prodrug for carbonic anhydrase inhibitor |
| abstract |
NEW MATERIAL: This compound is shown by formula I to formula III [Z is a water-soluble carrier; A is a group capable of maintaining carbonic anhydrase inhibiting activity and forming a bond enzymatically cleavable bond with Z when added to (a) 2-benzothiazosulfonamide, (b) hydroxy methazolamide or (c) dichlorphenamide]. n EXAMPLE: 6-[β-(Glucopyranosyl)oxyethoxy-2-benzothiazolesulfonamide. n USE: A prodrug for carbonic anhydrase inhibitor(CAI) useful for locally treating glaucoma, increased water solubility of CAI without exerting bad influence on CAI activity. n PROCESS: Especially a water-soluble carrier containing the whole OHs protected except a reaction site with A is reacted with a CAI analog of the substance (a) to (c) under a proper reaction condition and the Z protecting group is removed to give compounds of formula I to formula III. n COPYRIGHT: (C)1991,JPO |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H05507286-A |
| priorityDate |
1989-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |