http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H03128351-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e4feda2a82a4adcd92a7619df2248333 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e43b4ca6b41ce9f54c9a895d474c81a |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C279-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C277-08 |
| filingDate | 1990-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ee817871323559bf3cd88dda3a6a1c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e7ffa3d31f71ca2df4aeee9228e7801 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c95eb99a1530d855b0764cf64adf3f5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e104e9ab6cd7d26acb5c116b4c90c6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66a657a92a02a80cf2fa21b9571c6eb2 |
| publicationDate | 1991-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H03128351-A |
| titleOfInvention | Alpha type crystal of deoxyspergualin hydrochloride and production thereof |
| abstract | NEW MATERIAL:To obtain α type crystal of N-[4-(3-aminopropyl) aminobutyl]-2-(7-guanidinoheptanamide)-2-hydroxyethanamide trihydrochloride. n USE: Having excellent carcinostatic effects on various animal grafted cancers, further showing immunosuppressing action and useful as a drug having improved hygroscopicity, thermostability and excellent handleability. n PREPARATION: Powder of deoxyspergualin hydrochloride or hydrous syrup thereof is allowed to stand and/or blended while stirring at low humidity under a mild temperature condition to give the objective substance. The crystal is obtained by allowing to stand the substance at 0-30°C for 5-20 days, usually about 10 days. In the most practical method, a proper amount of preliminarily obtained α type crystal is seeded in hydrous syrup having ≤20% water content, stirred at ≤30% relative humidity, solidified in several hours, allowed to stand in desiccator in the presence of silica gel and crystallized to give the objective substance. n COPYRIGHT: (C)1991,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013525282-A |
| priorityDate | 1989-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.