http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H03127986-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e4feda2a82a4adcd92a7619df2248333 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 |
| filingDate | 1989-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83119a2079d3579572632f3cfc293802 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94c57550570ff5224a87c3897b1556fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c05a0184de4ede29e8d2d68253d8a8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2dad7835b554715a3228fb520363f3a1 |
| publicationDate | 1991-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H03127986-A |
| titleOfInvention | Novel nucleoside phosphorylase |
| abstract | PURPOSE: To obtain a nucleoside phosphorylase exhibiting specific physical and chemical properties and having the activities of purine as well as pyrimidine nucleoside phosphorylase. n CONSTITUTION: The nucleoside phosphorylase has the following physical and chemical properties I to VI. (I) Action: catalyzing the reaction of formula 1 (B is purine base or pyrimidine base; R is OH or H). (II) Substrate specificity: acting to purine nucleoside and 2'-deoxypurine nucleoside excluding xanthosine and acting to pyrimidine nucleoside and 2'-deoxypyrimidine nucleoside. (III) Optimum pH is about 8.0 and the compound is stable between pH6.5-9.0 by the treatment at 4°C for 24hr. (IV) The optimum temperature is about 40°C and the compound is stable up to 60°C by the treatment at pH7.0 for 30min. (V) Molecular weight: about 125,000 by gel-filtration and about 25,000 by sodium dodecyllaurylsulfate-polyacrylamide gel electrophoresis and the molecule is constituted of 5 subunits. (VI) Inhibitors: the compound is not inhibited by various SH-group modifier, alkylating agent, metal chelating agent and bivalent metal ion. n COPYRIGHT: (C)1991,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7629457-B2 |
| priorityDate | 1989-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 171.