http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H03127740-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-255 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-48 |
| filingDate | 1989-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f4428975e8c4f7a53f41cd09fd09215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f64e3fdfb5652ebcbb5329be5ed7ae9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c2587f92145bd66fd460ef0f29a92ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50bf2573d87ec93fd2060f88ec3b2b30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1140fe5228c2fe6e74684110a15da115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad260c19afd2a4635c0ade016fa1281f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7fd6d3ff6df5c948a0570683d1ec3cf |
| publicationDate | 1991-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H03127740-A |
| titleOfInvention | Remedy for malignant tumor |
| abstract | PURPOSE: To obtain a remedy for malignant tumor, having enhanced antitumor action on tumor necrosis factor(TNF), containing TNF and surfactant. n CONSTITUTION: A remedy for malignant tumor containing TNF including natural type, recombinant TNF and also TNF containing modified protein showing physiologically similar physiological activity as TNF and a surfactant such as Tween 20, sodium dodecyl sulfate or gum arabic as active ingredients. The preferable administration route is intravenous injection (including intravenous drip injection) of solution or suspension or administration in tumor and a dose of TNF is 1×10 4 -5×10 5 U/m 2 surface area of body/hr. Fluidity of cell membrane of tumor cell is increased by the surfactant, function of TNF is enhanced, further permeability of tumor cell is increased, nonspecific intake of TNF in cell is raised and antitumor effect is enhanced. n COPYRIGHT: (C)1991,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9301825-A1 |
| priorityDate | 1989-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.