http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H03118329-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ac1d45776a8a24b24fec258548e537 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L1-305 |
| filingDate | 1989-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09be82f679272978ceb8ccaa051ebe67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9007234a79b3fa6008e622b8ea286a8 |
| publicationDate | 1991-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H03118329-A |
| titleOfInvention | Hypotensive agent |
| abstract | PURPOSE: To obtain a hypotensive agent, containing a peptide fraction extracted from a sardine as an active ingredient, suppliable in a large amount at a low cost with high safety and utilizable also as foods. n CONSTITUTION: The objective substance obtained by extracting a sardine muscle with water, fractionating the resultant extract with a 70-100% saturated ammonium sulfate, hydrolyzing the prepared fraction with a protease (e.g. pepsin) at 37-45°C and pH2-3, providing a peptide fraction having 150-5000 molecular weight, subsequently, as necessary, subjecting the aforementioned fraction to gel filtration, affording a peptide fraction having 200-2000 molecular weight, then suitably blending the above-mentioned peptide fraction as an active ingredient with a normally used carrier, base and excipient and preparing a pharmaceutical according to a conventional method. The above-mentioned agent is preferably prepared in the form of oral administration, such as capsule, table, powder or granule. The dose thereof is 1.0-3000mg expressed in terms of the peptide fraction per day for an adult. n COPYRIGHT: (C)1991,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7358332-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0951837-B1 |
| priorityDate | 1989-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.