http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H03101668-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cef2a6d661df17e57ad3155c24188735 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D257-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D257-04 |
| filingDate | 1989-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a2fccbf9915adbcd7acbdbc5b023db7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d78c7b434d82c343f9ba945d7e5c28f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31dbea8a8250c13e10ece4c0130a10bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_443f792dead4f02fce768dc843777ba3 |
| publicationDate | 1991-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H03101668-A |
| titleOfInvention | Production of tazanolast |
| abstract | PURPOSE: To industrially advantageously obtain the title compound useful as an antiallergic agent having a purity sufficiently permissible as the raw material for medicine by reacting (A) 3-(1H-tetrazol-5-yl)aniline with (B) dibutyl oxalate in the presence of an acid. n CONSTITUTION: (A) 3-(1H-Tetrazol-5-yl)aniline is reacted with (B) dibutyl oxalate in the presence of (C) an acid, preferably hydrochloric acid, sulfuric acid or mixture thereof or one or more kinds of organic acids selected from oxalic acid, malonic acid, pyruvic acid and oxaloacetic acid, preferably at an amount of the ingredient B 5-10 times the ingredient A and an amount of the ingredient C 0.05-1.0 times, especially 0.3-0.4 times by mole based on the ingredient A at 80-100°C for 12-20hr and then the reaction product is purified, preferably by absorbing agent, especially an active alumina to provide butyl 3'-(1H- tetrazol-5-yl)oxanylate (tazanolast) with a high purity, high yield and good reproducibility. n COPYRIGHT: (C)1991,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007287879-A |
| priorityDate | 1989-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.