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filingDate 1989-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8e3199eebe6aeb5c5cec83549ec22d2
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publicationDate 1990-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H029897-A
titleOfInvention Teicoplanin hydrazide
abstract NEW MATERIAL: A compound o the formula [wherein Y is R 1 R 2 N-NR(wherein R is a 1-4 C alkyl; R 1 is H, a 1-4 C alkoxyl or the like; and R 2 is H, a 1-4 C alkyl or the like); A is H, -N- (10 or 11 C aliphatic acyl)β-D-deoxy-2- aminoglucopyranosyl; B is H or -acetyl-β-D-2-deoxy-2aminoglucopyranosyl; and M is H or α-D-mannopyranoxyl; provided that M is H when A and M are simultaneously H or when B is H and A is H] and a salt thereof. n EXAMPLE: Teicoplaninaglycon-1-methylhydrazide trifluoroacetate. n USE: Antibacterial agents. n PREPARATION: After the prim. amino group of teicoplanin as a starting material is protected, the material is reacted with a 3-6 molar time excess of a hydrazine of the formula: R 1 R 2 NNRH in the presence of a condensing agent (desirably diphenylphosphorazidate, etc.), in a polar aprotic solvent. n COPYRIGHT: (C)1990,JPO
priorityDate 1988-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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