http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0291059-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ead90443277482e25bf91bfddef2b5a7 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-08 |
| filingDate | 1988-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a35eac2d140d0b8baafd203585d95ff9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf40e91c73c59a1fe5584962a0df4683 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee3d8fcd0514ea73e49c5540b3f5c481 |
| publicationDate | 1990-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0291059-A |
| titleOfInvention | Production of 7-substituted indole compounds |
| abstract | PURPOSE: To industrially and regioselectively obtain the subject compounds useful as the raw materials, etc., for medicines in a simple process and in a good yield by using an indole compound having a specified substituent at 7-position as an intermediate. n CONSTITUTION: A compound of formula I [R 1 is -COR 3 (R 3 is monovalent group); R 2 is substituent; n is 0, 1-5] is used as an intermediate and a compound of formula II (R 4 is hydroxy or nitro) or formula III is obtained. The above reaction is carried out by using an N,N-dimethylformamide-water-based mixture solvent in the presence of copper sulfate.penta hydrate. The amount of copper sulfate.penta hydrate used is 1-10 equivalent, preferably order of 5 equivalent and the amount of the mixture solvent used is 5-40 pts.wt., preferably 15-30 pts.wt. The reaction temperature is 80-130°C, preferably order of 125°C. n COPYRIGHT: (C)1990,JPO&Japio |
| priorityDate | 1988-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.