http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0288578-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eebd94dd108d74a49ab9415252e5e281 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-397 |
| filingDate | 1988-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a451c2f6459b318657565ed00ec9e601 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d448c9c419de4f60739c4b05ef678b46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44156a1962b43e55c8f278087e978ade http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b123704a2b77b4a27c62ba70f6b927db |
| publicationDate | 1990-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0288578-A |
| titleOfInvention | Production or carbapenem compound |
| abstract | NEW MATERIAL:A carbapenem compound expressed by formula I (R 1 is protect ing group of carboxyl group: R 2 and R 3 are protecting groups of amino groups). n EXAMPLE: 4-Nitrobenzyl(1R,5S,6S)-[(R)-1-hydroxyethyl]-1-methyl-]1,2-di(4-nitrobenzyloxycarbonyl)pyrazolldin-4-yl]thiocarbapenem-3-carboxylate. n USE: Useful as an intermediate for compounds, expressed by formula V, having excellent antimicrobial activity and useful as an antimicrobial agent. n PREPARATION: A compound expressed by formula II is reacted with a metallic catalyst in an inert solvent and cyclized to provide an oxo compound expressed by formula III, which is then acylated and converted into a reactive derivative at the oxo group. The resultant compound is subsequently reacted with a mercaptopyrazolidine expressed by formula IV or a reactive derivative thereof to readily afford the compound expressed by formula I in good yield in one pot. n COPYRIGHT: (C)1990,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103570750-A |
| priorityDate | 1988-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.