Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df04cb3707bdee17679a7bd24ed2d643 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-546 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-06 |
filingDate |
1989-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0905662a6e0185a1307aef3a0b7e47b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd47bb5928adf9ca80f44662c2e134f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adefbd5c3f2608bdeea41c0d2edf98d9 |
publicationDate |
1990-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-H0285278-A |
titleOfInvention |
Active acylating agent |
abstract |
NEW MATERIAL:Compounds of formula I (R 2 is lower alkyl; Het is lower alkyl substituted tetrazolyl or tetrazolopyridazinyl). n EXAMPLE: 1-Methyltetrazol-5-yl 4-ethyl-2,3-dioxopiperazin-1-ylcarbonyl thiolate. n USE: An active acylating agent. Used for production of a kind of antibacterial agent (cephalosporin). n PREPARATION: 4-Ethyi-2,3-dioxopiperazinylcarbonyl chloride of formula 4 is reacted with 1-methyltetrazole-5-thiol of formula 5a to obtain an objective compound of formula 2. The yield is improved by carrying out the reaction using a novel tri-n-butyltin thiolate of formula 5b. n COPYRIGHT: (C)1990,JPO&Japio |
priorityDate |
1980-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |