http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0285278-A

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filingDate 1989-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0905662a6e0185a1307aef3a0b7e47b8
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publicationDate 1990-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H0285278-A
titleOfInvention Active acylating agent
abstract NEW MATERIAL:Compounds of formula I (R 2 is lower alkyl; Het is lower alkyl substituted tetrazolyl or tetrazolopyridazinyl). n EXAMPLE: 1-Methyltetrazol-5-yl 4-ethyl-2,3-dioxopiperazin-1-ylcarbonyl thiolate. n USE: An active acylating agent. Used for production of a kind of antibacterial agent (cephalosporin). n PREPARATION: 4-Ethyi-2,3-dioxopiperazinylcarbonyl chloride of formula 4 is reacted with 1-methyltetrazole-5-thiol of formula 5a to obtain an objective compound of formula 2. The yield is improved by carrying out the reaction using a novel tri-n-butyltin thiolate of formula 5b. n COPYRIGHT: (C)1990,JPO&Japio
priorityDate 1980-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 30.