http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0278681-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66a9d6f86e9d9803174d2a03d3cd24a3 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 |
| filingDate | 1988-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75f3d54c35ef1dd7a05b4f339e52ed04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e32ec0c34e1c20980630081387119f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26a4ac7c788967a714fc3e87a1360ee4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94771c3458e3c8892c0bead0e6fdc67a |
| publicationDate | 1990-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0278681-A |
| titleOfInvention | Novel alkaloid and hypotensor containing said alkaloid as active ingredient |
| abstract | NEW MATERIAL:A compound expressed by formula I [R represents lower alkyl; X represents N-CH 3 or N-CH(CH 3 ) 2 ; Y represents formula II or N- CH(CH 3 ) 2 ]. n EXAMPLE: (1β)-7-Ethoxy-6,6',12-trimethoxy-2'-isopropyl-2-methylberbamane. n USE: A hypotensor. n PREPARATION: Stephania tetrandra S.Moore is extracted with water, alcohols, etc., and the solvent is removed from the resultant extract to from a residue, which is then dissolved in a mixed solvent of water with the alcohols and distributed with an organic solvent such as n-hexane. After removing a fat-soluble component transferred to the organic solvent, it is dissolved in water, aqueous ammonia and further extracted with chloroform, etc., to afford an extract. Then the organic solvent extract is subjected to column chromatography by using water, methanol, etc., as an eluting solvent to afford a composed expressed by formula III (A represents H or CH 3 ), which is then dissolved in a solvent such as methanol and converted to an N-oxide using an oxidizing agent such as aqueous hydrogen peroxide. n COPYRIGHT: (C)1990,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112608328-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112608328-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112552308-A |
| priorityDate | 1988-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.