http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0267295-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-708 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-16 |
| filingDate | 1989-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_362088a8071c40180f4dd41e0c4a8976 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d27555e28e82452f12799703dd9c30f |
| publicationDate | 1990-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0267295-A |
| titleOfInvention | Purine derivative |
| abstract | NEW MATERIAL: A compd. represented by formula I (wherein R is Cl, a lower alkoxy, a lower alkylthio or a mono lower alkylamino). n EXAMPLE: 2-Amino-6-chloro-9-(2,3-dideoxy-2-fluoro-β-D-threopesitofuranosil)-9H- purine. n USE: This new material is an antiviral agent and especially useful as the treatment and prevention of retrovirus infection, for example, HIV. n PROCESS: A compd. represented by formula II (R 1 is alloyl) is treated with, for example ammonia to cleave a group R 1 to obtain a compd. represented by formula I (wherein R is Cl). The compd. represented by formula II is a novel substance and can be produced by a method wherein a group 2 is cloven from a compd. represented by formula IV obtained by reacting 2-amino-6-chloropurine with a compd. represented by formula III (R 2 is alloyl) to obtain a compd. represented by formula V and this compd. is reacted with phenoxythiocarbonyl chloride to obtain a compd. represented by formula VI and this compd. is reacted with tributyltin hydride in the presence of a free radical initiator. n COPYRIGHT: (C)1990,JPO |
| priorityDate | 1988-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.