http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0265792-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_52a65b677bbedbe7bf090dd556a7cc43 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 |
| filingDate | 1988-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aacb6815cdc2a59d81a0068c10a8aa20 |
| publicationDate | 1990-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0265792-A |
| titleOfInvention | Production of optically active peptide by modified enzyme |
| abstract | PURPOSE: To efficiently obtain a series of the subject peptides by carrying out coupling reaction of an ester of a specific amino acid or peptide with a D-amino acid ester in a water-immiscible organic solvent using a specific enzyme. n CONSTITUTION: (A) An ester of an amino acid or peptide, expressed by formula I (X is acyl type protecting group; A 1 is amino acid residue; R 1 is alkyl) and having the N-terminal protected with an acyl group as the first substrate and (B) a D-amino acid ester expressed by formula II (A 2 is amino acid residue; R 2 is alkyl) as the second substrate are dissolved in a water-immiscible organic solvent, such as benzene or toluene, and then mixed with a solution of an enzyme which is a modified thiol protease in a solvent to carry out coupling reaction and introduce amino acid which is the D-isomer. Thereby, the objective optically active peptide is obtained. n COPYRIGHT: (C)1990,JPO&Japio |
| priorityDate | 1988-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 17.