http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0259559-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_630b360599ea5cf4b5bcbc0c6c0a3e2d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 |
| filingDate | 1988-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b77dda87e4256825b061715bb610ea0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecde6b5f9cc367bb380a5faf5ac789fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9be47b39d6045c1565abf9b2c300c584 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bde50daecafb6f30f70a9e6e7b71d6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30549f70ba543ad0aabf2a2320c94d58 |
| publicationDate | 1990-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H0259559-A |
| titleOfInvention | Pyridone derivative or salts thereof |
| abstract | NEW MATERIAL:A compound expressed by formula I (R 1 is H, cyano, carboxyl, lower alkoxycarbonyl, carbamoyl, NO 2 , NH 2 or halogen; R 2 is H or lower alkyl; R 3 to R 5 are H, lower alkoxy or OH or any two thereof together may form methylenedioxy or ethylenedioxy; m and n are 0-4; A is single bond when n is 0 and imino when n is 1-4) or salts thereof. n USE: A Cardiotonic agent. n PREPARATION: A carboxylic acid expressed by formula II is reacted with a compound expressed by formula III (G is H when n is 0 and amino when n is 1-4) according to an amide bond forming reaction to afford the compound expressed by formula I. A mixed acid anhydride method for, i.e., reacting the carboxylic acid expressed by formula II with an alkylhalocarboxylic acid to provide a mixed acid anhydride and then reacting the resultant mixed acid anhydride with an amine is the most preferred method for forming amide bonds. The reaction temperature is about -20 to +100°C and reaction time is 5-10hr. n COPYRIGHT: (C)1990,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10112939-B2 |
| priorityDate | 1988-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.