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filingDate 1988-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9394a6a88a8f62db50d038c138b1083e
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publicationDate 1990-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H0256429-A
titleOfInvention External drug containing morphines
abstract PURPOSE: To obtain an external drug containing morphines having improved transcutaneous absorptivity and useful for reducing the pain after operation, etc., by adding a specific amount of a medium-chain fatty acid monoglyceride based on the whole weight of the drug. n CONSTITUTION: The objective drug contains ≥25wt.% of a medium-chain fatty acid monoglyceride (e.g., glycerol monooctanoate) based on the whole weight of the drug preparation. The amount of the medium-chain fatty acid monoglyceride is 25-99.95wt.% based on 0.05-10wt.% of morphines. The morphines (e.g., morphine hydrochloride, morphine sulfate or normorphine) may be used singly or as a mixture. The drug may be arbitrarily incorporated with other additives provided that the ratio of the morphines to the medium- chain fatty acid monoglyceride is maintained within the above range. n COPYRIGHT: (C)1990,JPO&Japio
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